European Interdisciplinary Guidelines on Pain Management in Acute Pancreatitis

UEG, EPC, EDS, ESDO, EAGEN, ESPGHAN, ESGAR, and ESPCG evidence-based recommendations

This project is funded by a UEG Guideline Development Grant.

Project Leadership

  • Sanjay Pandanaboyana, Consultant HPB and Transplant Surgeon, Freeman Hospital, Newcastle, UK ( 
  • Asbjörn Drewes, Professor and Chief Physician, Dept. of Gastroenterology and Hepatology, Aalborg University Hospital, Aalborg, Denmark (

Rationale for the Guideline

  • Incidence of acute pancreatitis is increasing 3% annually
  • Pain is the most relevant dimension of the patient experience in AP
  • Pain is a diagsnotic criteria for AP based on the Revised Atlanta Criteria

Supporting Societies

The EPC has invited UEG Member Societies as well as other Specialist Member Societies to collaborate on this project. The following societies have confirmed their participation

  • UEG - United European Gastroenterology (sponsor)
  • EPC - European Pancreatic Club (lead society)
  • EDS - European Digestive Surgery
  • ESDO - European Society of Digestive Oncology
  • EAGEN - European Association for Gastroenterology, Endoscopy, and Nutrition
  • ESGAR - European Society of Gastrointestinal and Abdominal Surgery
  • ESPCG - European Society for Primary Care Gastroenterology

Steering Committee

Sanjay Pandanaboyana (UK) Asbjörn Mohr Drewes (DK)
Enrique de-Madaria (ES) Gabriele Capurso (IT)
Juan-Enrique Dominguez-Munoz (ES) Matthias Löhr (SE)
Hanna Sternby (SE) Sara Regner (SE)
Jonas Rosendahl (DE) Linda Sharp (UK)
Giovanni Marchegiani (IT) Heiko Witt (DE)
Sören S. Olsen (DK) Stefan A.W. Bouwense (NL)
Louise Kuhlmann (DK) Maisam Abu-El-Heija (USA)
Cecilie Siggaard Knoph (DK) (PhD student)  


  • Stefanos Bonovas, Associate Professor of Medical Statistics, Humanitas University, Milan, Italy
  • Daniele Piovani, Assistant Professor of Medical Statistics, Humanitas University, Milan, Italy

Approach - UEG Framework for the Development of High Quality Guidelines

Source: UEG Journal, Volume: 8, Issue: 8, Pages: 851-864, first published: 01 October 2020, DOI: (10.1177/2050640620950854) (LINK)

Link to the presentation held at the kick-off meeting at UEG Week 2023

Project Timelines (January to June 2024)

  1. Finalize working group members and leads
  2. Project introduction and methodology training (Feb. 2024)
  3. Define preliminary PICO questions for each chapter
  4. Evaluation of PICO questions by patient association representatives
  5. Define final set of PICO questions
  6. Literature review
  7. Consensus process for each PICO question
  8. Face-to-face meeting at the 2024 annual EPC meeting in Santiago de Compostela