One of the pillars of the Pancreas 2000 program is to work in a project group and conduct scientific research and/or a clinical trial, which ideally ends in a publication. Below you will find a list of papers that were published as a direct result of the Pancreas 2000 program. 

Moreover, the Pancreas 2000 program has led to more publications in the field of Pancreatology overall. Based on a search conducted in 2018, course graduates have published over 2,523 articles relating to the pancreas, thereby making an important contribution to the further development of this important specialty.



  1. Pancreatic Cancer
  2. Acute and Chronic Pancreatitis
  3. Pancreatic Neuroendocrine Tumors
  4. Pancreatic Surgery
  5. Other Topics

Pancreatic Cancer

Recent Discoveries of Diagnostic, Prognostic and Predictive Biomarkers for Pancreatic Cancer Khomiak A, Brunner M, Kordes M, Lindblad S, Miksch R, Öhlund D, Regel DOI: 10.3390/cancers12113234

The quality of pain management in pancreatic cancer: A prospective multi-center study Damm M, Weniger M, Kölsch AK, Lampert C, Ceyhan G, Beer S, Schorn S, Moir J, Michl P, Rosendahl J DOI: 10.1016/j.pan.2020.08.017

Neoadjuvant therapy in elderly patients receiving FOLFIRINOX or gemcitabine/nab-paclitaxel for borderline resectable or locally advanced pancreatic cancer is feasible and lead to a similar oncological outcome compared to non-aged patients - Results of the RESPECT-Study Weniger M, Moir J, Damm M, Maggino L, Kordes M, Rosendahl J, Ceyhan G, Schorn S, RESPECT study group DOI:10.1016/j.surojnc.2020.08.031

In the Era of the Leeds Protocol: A Systematic Review and a Meta-Analysis on the Effect of Resection Margins on Survival Among Pancreatic Ductal Adenocarcinoma Patients Kurlinkus B, Ahola R, Zwart E, Halimi A, Yilmaz BS, Ceyhan GO, Laukkarinen J. Scand J. Surg. 2020 Mar;109(1):11-17.

Risk of Malignancy in Resected Pancreatic Mucinous Cystic Neoplasms Keane MG, Shamali A, Nilsson LN, Antila A, Millastre Bocos J, Marijinissen Van Zanten M, Verdejo Gil C, Maisonneuve P, Vaalavuo Y, Hoskins T, Robinson S, Ceyhan GO, Abu Hilal M, Pereira SP, Laukkarinen J, Del Chiaro M Br J Surg. 2018 Mar;105(4):439-446. doi: 10.1002/bjs.10787.

Real-World Clinical Practice of Intensified Chemotherapies for Metastatic Pancreatic Cancer: Results From A Pan-European Questionnaire Study Le N, Vinci A, Schober M, Krug S, Javed MA, Kohlmann T, Sund M, Neesse A, Beyer G Digestion. 2016;94(4):222-229. doi: 10.1159/000453257. Epub 2016 Dec 29.

Prognostic and Predictive Markers in Pancreatic Adenocarcinoma Le N, Sund M, Vinci A; GEMS Collaborating Group of Pancreas 2000 Dig Liver Dis. 2016 Mar;48(3):223-30. doi: 10.1016/j.dld.2015.11.001. Epub 2015 Nov 14.

Nature and Management of Pancreatic Mucinous Cystic Neoplasm (MCN): A Systematic Review of the Literature Nilsson LN, Keane MG, Shamali A, Millastre Bocos J, Marijinissen van Zanten M, Antila A, Verdejo Gil C, DelChiaro M, Laukkarinen J. Pancreatology. 2016 Nov - Dec;16(6):1028-1036. doi: 10.1016/j.pan.2016.09.011. Epub 2016 Sep 20.

New Advances in the Treatment of Metastatic Pancreatic Cancer
Schober M, Javed MA, Beyer G, Le N, Vinci A, Sund M, Neesse A, Krug S
Digestion. 2015;92(3): 175-84

Increased Incidence of Extrapancreatic Neoplasms in Patients with IPMN: Fact or Fiction? A Critical Systematic Review
Pugliese L, Keskin M, Maisonneuve P, D'Haese JG, Marchegiani G, Wenzel P, Del Chiaro M, Ceyhan GO.
Pancreatology. 2015 May-Jun; 15(3):209-16/j.pan.2015.03.007. Epub 2015 Mar 18.

Association Between Pancreatic Intraductal Papillary Mucinous Neoplasms and Extrapancreatic Malignancies 
Marchegiani G, Malleo G, D'Haese JG, Wenzel P, Keskin M, Pugliese L, Borin A, Benning V, Nilsson L, Oruc N, Segersvard R, Friess H, Schmid R, Löhr M, Maisonneuve P, Bassi C, Ceyhan GO, Salvia R, Del Chiaro M. 
Clin Gastroenterol Hepatol 2015 Jun; 13(6): 1162-9. doi. 10.1016/j.cgh.2014.11.029. Epub 2014 Dec 2.

Influence of Cachexia and Sarcopenia on Survival in Pancreatic Ductal Adenocarcinoma: A Systematic Review Ozola Zalite I, Zykus R, Francisco Gonzalez M, Saygili F, Pukitis A, Gaujoux S, Charnley RM, Lyadov V Pancreatology. 2015 Jan-Feb;15(1):19-24. doi: 10.1016/j.pan.2014.11.006. Epub 2014 Dec 4.

Pancreaticduodenectomy for Peri-Ampullary Neoplasia Leads to Specific Micronutrient Deficiencies Armstrong T, Strommer L, Ruiz-Jasbon F, Shek FW, Harris SF, Permert J, Johnson CD Pancreatology. 2007;7(1):37-44. Epub 2007 Apr 18.

Does Anyone Survive Pancreatic Ductal Adenocarcinoma? A Nationwide Study Re-Evaluating the Data of the Finnish Cancer Registry Carpelan-Holmström M, Nordling S, Pukkala E, Sankila R, Lüttges J, Klöppel G, Haglund C. Gut. 2005 Mar;54(3):385-7.

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Acute and Chronic Pancreatitis

Serum levels of advanced glycation end products and their receptors sRAGE and Galectin-3 in chronic pancreatitis. Böhme R, Becker C, Keil B, Damm M, Rasch S, Beer S, Schneider R, Kovacs P, Bugert P, Riedel J, Griesmann H, Ruffert C, Kaune T, Michl P, Hesselbarth N, Rosendahl J Pancreatology. 2019 Dec 17. pii: S1424-3903(19)30810-5. doi: 10.1016/j.pan.2019.12.013. [Epub ahead of print]

Mean Muscle Attenuation Correlates With Severe Acute Pancreatitis Unlike Visceral Adipose Tissue and Subcutaneous Adipose Tissue Sternby H, Mahle M, Linder N, Erichson-Kirst L, Verdonk R, Dimova A, Ignatavicius P, Ilzarbe L, Koiva P, Penttilä A, Regnér S, Bollen TL, Brill R, Stangl F, Wohlgemuth WA, Singh V, Busse H, Michl P, Beer S, Rosendahl J United European Gastroenterol J. 2019 Dec;7(10):1312-1320. doi: 10.1177/2050640619882520. Epub 2019 Oct 9.

Statin Use is Not Associated with an Increased Risk of Acute Pancreatitis - A Meta-Analysis of Observational Studies Poropat G, Archibugi L, Korpela T, Cardenas-Jaen K, de-Madaria E, Capurso G United European Gastroenterol J. 2018 Oct;6(8):1206-1214. doi: 10.1177/2050640618781168. Epub 2018 May 31.

Intestinal Fatty Acid Binding Protein as a Marker of Necrosis and Severity in Acute Pancreatitis Kapcinskas J, Gedgaudas R, Hartman H, Sippola T, Lindström O, Johnson CD, Regnér S Pancreas. 2018 Jul;47(6):715-720. doi: 10.1097/MPA.0000000000001068.

Short Article: Presence, Extent, and Location of Pancreatic Necrosis Are Independent of Aetiology in Acute Pancreatitis
Verdonk RC, Sternby H, Dimova A, Ignatavicius P, Koiva P, Penttila AK, Ilzarbe L, Regner S, Rosendahl J, Bollen TL
Eur J Gastroenterol Hepatol 2018 Mar; 30(3): 342-345. doi: 10.1097

Analysis of Lifestyle Factors in Patients with Concomitant Chronic Pancreatitis and Liver Cirrhosis
Aghdassi AA, Schneider A, Kahl M, Schütte K, Kuliaviene I, Salacone P, Lutz J, Tuklainen E, Simon P, Schauer B, Uomo G, Hauge T, Ceyhan GO
Pancreatology. 2017 Sep-Oct; 17(5): 698-705. doi: 10.1016/j.pan.2017.07.194. Epub 2017 Jul 31. 

Deficiency of Fat-Soluble Vitamins in Chronic Pancreatitis: A Systematic Review and Meta-Analysis Martinez-Moneo E, Stigliano S, Hedström A, Kaczka A, Malvik M, Waldthaler A, Maisonneuve P, Simon P, Capurso G Pancreatology. 2016 Nov - Dec;16(6):988-994. doi: 10.1016/j.pan.2016.09.008. Epub 2016 Sep 20.

Chronic Pancreatitis: Do Serum Biomarkers Provide An Association With an Inflammageing Phenotype? Rasch S, Valantiene I, Mickevicius A, Beer S, Rosendahl J, Charnley RM, Robinson SM Pancreatology. 2016 Sep-Oct;16(5):708-14. doi: 10.1016/j.pan.2016.08.004. Epub 2016 Aug 8.

Significant Inter-Observer Variation in the Diagnosis of Extrapancreatic Necrosis and Type of Pancreatic Collections in Acute Pancreatitis. An International Multicenter Evaluation of the Revised Atlanta Classification Sternby H, Verdonk RC, Aguilar G, Dimova A, Ignatavicius P, Ilzarbe L, Koiva P, Lantto E, Loigom T, Penttilä A, Regnér S, Rosendahl J, Strahinova V, Zackrisson S, Zviniene K, Bollen TL Pancreatology. 2016 Sep-Oct;16(5):791-7. doi: 10.1016/j.pan.2016.08.007. Epub 2016 Aug 13.

Does Glyceryl Nitrate Prevent Post-ERCP Pancreatitis? A Prospective, Randomized, Double-Blind Placebo-Controlled Multicenter Trial Nojgaard C, Hornum M, Elkjaer M, Hjalmarsson C, Heyries L, Hauge T, Bakkevold K, Andersen PK, Matzen P, European Post-ERCP Pancreatitis Preventing Study Group Gastrointest Endosc. 2009 May;69(6):e31-7. doi: 10.1016/j.gie.2008.11.042.

Impact of Chronic and Acute High-Fat Feeding on Acute Experimental Pancreatitis Complicated by Endotoxinaemia
Segersvärd R, Sylvan M, Lempinen M, Larsson J, Permert J
Scand J Gastroenterol. 2004 Jan; 39(1): 74-80

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Pancreatic Neuroendocrine Tumors

Reappraisal of a 2-Cm Cut-Off Size for the Management of Cystic Pancreatic Neuroendocrine Neoplasms: A Multicenter International Study Maggino, L, Schmidt A, Käding A, Westermark S, Ceppa EP, Falconi M, Javed AA, Landoni L, Pergolini I, Perinel J, Vollmer CM Jr, Sund M, Gaujoux S, on behalf of the Pancreas 2000 research group Ann Surg. 2019 Jul 24. doi: 10.1097/SLA.0000000000003508. [Epub ahead of print]

Prognosis of Sporadic Resected Small (≤2 cm) Nonfunctional Pancreatic Neuroendocrine Tumors A Multi-Institutional Study Sallinen VJ, Le Large TTY, Tieftrunk E, Galeev S, Kovalenko Z, Haugvik SP, Antila A, Franklin O, Martinez-Moneo E, Robinson SM, Panzuto F, Regenet N, Muffatti F, Partelli S, Wiese D. Ruszniewski P, Dousset B, Edwin B, Bartsch DK, Sauvanet A, Massimo F, Ceyhan GO, Gaujoux S; Pancreas 2000 research group HPB (Oxford). 2018 Mar;20(3):251-259. doi: 10.1016/j.hpb.2017.08.034. Epub 2017 Oct 5

Risk and Protective Factors for the Occurrence of Sporadic Pancreatic Endocrine Neoplasms Valente R, Hayes AJ, Haugvik SP, Hedenström P, Siuka D, Korsaeth E, Kämmerer D, Robinson SM, Maisonneuve P, Delle Fave G, Lindkvist B, Capurso G Endocr Relat Cancer. 2017 Aug;24(8):405-414. doi: 10.1530/ERC-17-0040. Epub 2017 May 31.

Surveillance Strategy for Small Asymptomatic Non-Functional Pancreatic Neuroendocrine Tumors A Systematic Review and Meta-Analysis Sallinen V, Le Large TY, Galeev S, Kovalenko Z, Tieftrunk E, Araujo R, Ceyhan GO, Gaujoux S HPB (Oxford). 2017 Apr;19(4):310-320. doi: 10.1016/j.hpb.2016.12.010. Epub 2017 Feb 21.

Diabetes, Smoking, Alcohol Use, and Family History of Cancer as Risk Factors for Pancreatic Neuroendocrine Tumors: A Systematic Review and Meta-Analysis Haugvik SP, Hedenström P, Korsaeth E, Valente R, Hayes A, Siuka D, Maisonneuve P, Gladhaug IP, Lindkvist B, Capurso Neuroendocrinology. 2015;101(2):133-42. doi: 10.1159/000375164. Epub 2015 Jan 22.

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Pancreatic Surgery

Systematic Review with Meta-Analysis: Endoscopic and Surgical Resection for Ampullary Lesions Christian Heise, Einas Abou Ali, Dirk Hasenclever, Francesco Auriemma, Aiste Gulla, Sara Regner, Sébastien Gaujoux, and Marcus Hollenbach J. Clin Med. 2020 Nov 10;9(11):E3622. Doi: 10.3390/jcm9113622

Pancreaticduodectomy for Peri-Ampullary Neoplasia Leads to Specific Micronutrient Deficiencies Armstrong T, Strommer L, Ruiz-Jasbon F, Shek FW, Harris SF, Permert J, Johnson CD Pancreatology. 2007; 7(1):37-44. Epub 2007 Apr 18. 

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Other Topics

Increased Prevalence of Subclinical Hypothyroidism in Common Bile Stone Patients Laukkarinen J, Kiudelis G, Lempinen M, Raty S, Pelli H, Sand J, Kemppainen E, Haglund C, Nordbäck I J Clin Endocrinol Metab. 2007 Nov;92(11):4260-4. Epub 2007 Aug 28.

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